There are MANY Style Guides available, but MOST publishing houses rely on the Chicago Manual of Style for answers to Grammatical, Formatting, and all things WRITING.
NOTE: DO be sure to check and see if the Publisher you are submitting your work to has THEIR Style Guide listed and conform to THAT.
Spell-Check programs and other programs that can help you CANNOT always be relied on.
Be sure to have this RECOMMENDED Dictionary on hand during your editing process.
Don't let your writing remain in the 20th Century.
This resource will make sure you aren't using archaic words, as well as helping your keep your writing RELEVANT.
While the majority of GRAMMAR Style is included in The Chicago Manual of Style, this great resource is helpful, and should always be with your writing tools.